Revolutionizing Regenerative Medicine

Unlock The Potential Of Your Body's Own Healing Mechanisms With SPL Therapy.

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Trichology

Elevating hair restoration with advanced regenerative therapy.

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Aesthetics

Unleashing the power of regeneration for radiant, youthful skin.

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Orthopaedics

Pioneering regenerative solutions for stronger, healthier joints.


SONICATED PLATELELT LYSATE (SPL) CONTAIN HIGHER LEVELS OF GROWTH FACTORS COMPARED TO PRP & GFC.

 

To understand why PRP sonicates mediated better effects in inducing hair follicle activation and SKP survival, and analyzed the level of growth factors in different PRP preparations [(Calcium-induced PRP (PC), Sonicated PRP without centrifugation ( PS), and Sonicated PRP with centrifugation ( PSS)] via an antibody-based protein array. The results indicated that out of 41 growth factors analyzed, 16 factors showed higher levels (≥2 folds) in PSS than in PC, which included VEGF-D, PDGF-AA, PDGF-BB, PDGF-AB, HGF, SCF, GDNF, FGF-4, FGF-7, bFGF, and IGF-1. The results suggest that sonication better release growth factors from platelets in PRP compared to conventional calcium-induced platelet contraction.

“Sonicated Platelet Lysate enriched (SPL) with 41 important GFCs that promotes Skin-derived precursors (SKPs) survival”.


 

Early research paints an optimistic picture:

  • In vitro studies: Sonicated Platelets demonstrably increases the proliferation and survival of hair follicle stem cells (SKPs) compared to conventional PRP.

  • Animal models: Studies in mice suggest improved hair growth and denser fur after onicated Platelets injections.

  • Sonicated Platelet Lysate activate hair follicle stem cells and mediates enhanced hair follicle regeneration